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Published on: August 8, 2022

Pregnancy Management and Outcomes with Hypertrophic Cardiomyopathy

Adhya Mehta1, Sarah Schumacher2, Rebekah Alison Bhansali3

  • 1Inova Health System, Falls Church, Virginia, USA.

CJC Open
|June 22, 2026
PubMed

Insights

Pregnancy in women with hypertrophic cardiomyopathy (HCM) requires careful management due to potential cardiovascular risks. Standardized care and further research are crucial for optimizing outcomes for both mother and fetus.

Area of Science:

  • Cardiology
  • Genetics
  • Maternal-Fetal Medicine

Background:

  • Hypertrophic cardiomyopathy (HCM) is a prevalent inherited cardiac condition.
  • Increasing diagnosis in women of childbearing age due to genetic testing and screening.
  • Pregnancy can present unique challenges and risks for women with HCM.

Purpose of the Study:

  • To review the specific challenges of managing hypertrophic cardiomyopathy during pregnancy.
  • To highlight the need for standardized protocols and multicentric studies.
  • To improve maternal and fetal outcomes in pregnant women with HCM.

Main Methods:

  • Literature review focusing on hypertrophic cardiomyopathy in pregnancy.
  • Analysis of current management practices and existing research.
  • Identification of knowledge gaps and areas for future research.

Main Results:

  • Most women with HCM tolerate pregnancy, but risks of heart failure and arrhythmias exist.
  • Adverse maternal and fetal outcomes are possible, especially with suboptimal health.
  • Medical therapy is the primary treatment; invasive procedures have limited data in pregnancy.

Conclusions:

  • Management of HCM in pregnancy is complex and varies across centers.
  • There is a significant need for large-scale, multicentric studies.
  • Standardized care protocols are essential to optimize outcomes for pregnant women with HCM and their infants.

Keywords:
hypertrophic cardiomyopathypregnancy

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