julius seizure acts within teashirt -expressing neurons to protect Drosophila melanogaster from bang-sensitivity

Loss of function in the Drosophila melanogaster gene julius seizure ( jus ) causes the fly to have a seizure-like condition known as bang-sensitivity. Here, we characterize the expression patterns of two different jus reporters, a jus -GAL4 construct and a jus protein trap allele, in the central nervous system during the developmental stages that jus expression is required. The majority of cells that expressed the jus -GAL4 construct co-expressed a GAL80 enhancer trap in the homeotic gene teashirt ( tsh ); expression of jus in this subpopulation was necessary to prevent bang-sensitivity.