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Reproductive Planning and Preconception Counseling in Kidney Disease (REPKID):A Cross-Sectional Survey
Gwendolyn Lee1, Maha Al Baghdadi2, Yaquelin Arevalo Iraheta2,3
1Department of Medicine, University of California, Los Angeles, CA.
Kidney Medicine
|June 22, 2026
Summary
Preconception counseling (PCC) for chronic kidney disease (CKD) patients is suboptimal, with 26% not receiving it. While PCC increases fertility concerns, it decreases knowledge about pregnancy with CKD.
Area of Science:
- Nephrology
- Maternal-Fetal Medicine
- Public Health
Background:
- Chronic kidney disease (CKD) significantly elevates risks for adverse maternal and fetal outcomes during pregnancy.
- Preconception counseling (PCC) is crucial for optimizing health and mitigating risks before pregnancy, yet its use in CKD populations is understudied.
Purpose of the Study:
- To determine the utilization and impact of preconception counseling (PCC) among patients with chronic kidney disease (CKD).
- To identify factors associated with PCC receipt and its effect on patient knowledge and concerns.
Main Methods:
- A survey-based study involving 108 female patients aged 18-45 with CKD at an urban academic nephrology clinic.
- Data collected on demographics, CKD history, PCC exposure, understanding, and healthcare interactions.
- Cross-sectional analysis using chi-squared/Fisher exact tests and logistic regression to assess PCC receipt and associated characteristics.
Main Results:
- 74% of surveyed CKD patients reported receiving preconception counseling (PCC).
- PCC from maternal-fetal medicine specialists covered more comprehensive topics like medication safety and complications.
- PCC recipients showed increased concern about fertility but paradoxically less knowledge regarding preconception and pregnancy with CKD.
Conclusions:
- Preconception counseling (PCC) for chronic kidney disease (CKD) patients remains suboptimal, with a significant portion not receiving this vital service.
- Disparities in discussion topics between maternal-fetal medicine and nephrology highlight the need for standardized PCC protocols.
- Ensuring equitable access to multidisciplinary specialists is essential for improving preconception care in CKD patients.
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