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Related Concept Videos

Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
Glaucoma: Overview01:25

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...

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Related Experiment Video

Updated: Jun 23, 2026

Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis
07:24

Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis

Published on: February 6, 2021

Exogenous Fusarium Endophthalmitis: Clinical Features, Treatment Modalities, and Visual Outcomes.

Sujin Kang1, William E Smiddy1, Nicolas A Yannuzzi1

  • 1Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida, United States.

Investigative Ophthalmology & Visual Science
|June 22, 2026
PubMed
Summary

Exogenous Fusarium endophthalmitis is a severe eye infection that often leads to poor vision despite aggressive treatment. Early detection and prompt antifungal therapy are crucial for improving outcomes in these challenging cases.

Related Experiment Videos

Last Updated: Jun 23, 2026

Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis
07:24

Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis

Published on: February 6, 2021

Area of Science:

  • Ophthalmology
  • Infectious Diseases
  • Microbiology

Background:

  • Exogenous Fusarium endophthalmitis is a rare but devastating intraocular infection.
  • Prompt diagnosis and treatment are critical for visual preservation.

Purpose of the Study:

  • To analyze the clinical characteristics, treatment strategies, and visual results of Fusarium endophthalmitis.
  • To evaluate outcomes in patients managed at a tertiary care center.

Main Methods:

  • Retrospective case series of 14 eyes with culture-proven Fusarium endophthalmitis.
  • Review of clinical data including demographics, presentation, treatment, and outcomes.
  • Analysis of visual acuity, intraocular pressure, and complications.

Main Results:

  • Infection sources included trauma, surgery, and contact lens use.
  • All patients required combined medical and surgical antifungal treatment.
  • Poor visual outcomes were common, with a median BCVA of 2.25 logMAR at follow-up.
  • Complications such as glaucoma and retinal detachment occurred frequently.

Conclusions:

  • Fusarium endophthalmitis necessitates aggressive, multimodal treatment with significant surgical intervention.
  • Long-term visual prognosis remains guarded despite comprehensive management.
  • Emphasizing early recognition and timely antifungal intervention is vital.