Related Experiment Video
Updated: Jun 23, 2026

Gene Regulation and Targeted Therapy in Gastric Cancer Peritoneal Metastasis: Radiological Findings from Dual Energy CT and PET/CT
Published on: January 22, 2018
99m Tc-FAPI SPECT/CT Provides Superior Diagnostic Performance to 18 F-FDG in Poorly Differentiated Gastric
Mohammad Hadi Samadi1, Kamran Aryana1, Ehsan Soltani2
1Nuclear Medicine Research Center.
Abstract:
We present the case of a 52-year-old woman with a history of poorly differentiated gastric adenocarcinoma who developed early satiety after gastrectomy and chemotherapy. Her CT and FDG PET/CT did not clearly show recurrence, but the 99m Tc-FAPI SPECT/CT scan detected all peritoneal and omental metastatic deposits with excellent clarity. Because FAPI targets activated stromal tissue, it is especially effective in poorly differentiated and mucinous tumors with limited FDG uptake. In this patient, FAPI revealed small peritoneal lesions missed by other imaging, highlighting its important role in detecting recurrence and guiding management.
Related Concept Videos
Positron Emission Tomography
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body being...
Imaging Studies II: Positron Emission Tomography and Scintigraphy
Fundamental Principles of PET
![An Automated Radiosynthesis of [68Ga]Ga-FAPI-46 for Routine Clinical Use](/_next/image?url=https%3A%2F%2Fcloudfront.jove.com%2FCDNSource%2Fteasers%2F66708.jpg&w=3840&q=50)
![Automated Preparation of [68Ga]Ga-3BP-3940 on a Synthesis Module for PET Imaging of the Tumor Microenvironment](/_next/image?url=https%3A%2F%2Fcloudfront.jove.com%2FCDNSource%2Fteasers%2F68356.jpg&w=3840&q=50)