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Related Experiment Video

Updated: Jun 24, 2026

A High-Throughput Image-Guided Stereotactic Neuronavigation and Focused Ultrasound System for Blood-Brain Barrier Opening in Rodents
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Focused Ultrasound System Design Considerations Based on the Applications for the Peripheral Nervous System.

Hannaneh Mahdavi, Ehsan Naeemi, Trevor Overton

    IEEE Transactions on Bio-Medical Engineering
    |June 22, 2026
    PubMed
    Summary
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    Focused ultrasound (FUS) systems for peripheral nervous system (PNS) applications require careful design. Addressing challenges in transducers, imaging, and miniaturization is key for clinical translation of peripheral FUS (pFUS).

    Area of Science:

    • Biomedical Engineering
    • Neurology
    • Medical Devices

    Background:

    • Focused ultrasound (FUS) shows promise for peripheral nervous system (PNS) applications.
    • Effective therapeutic outcomes depend on system design tailored to PNS targets.

    Purpose of the Study:

    • To review design considerations for FUS systems in PNS applications.
    • To link application requirements with hardware realizability for peripheral FUS (pFUS).

    Main Methods:

    • Literature review of FUS in the PNS.
    • Extraction of treatment parameters, transducers, and circuit characteristics.

    Main Results:

    • Overview of peripheral FUS (pFUS) capabilities and applications.
    • Analysis of transducer technologies and circuit designs.

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    Last Updated: Jun 24, 2026

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    Published on: July 16, 2020

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  • Understanding how PNS targets influence pFUS system design.

    • Conclusions:

    • Key challenges include transducer limitations, real-time imaging needs, miniaturization, and standardization.
    • Future research should focus on phased-array transducers, integrated circuits, advanced imaging, and AI.
    • A design-centric approach considering nerve properties is essential for innovative pFUS systems.