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Engaging Community Oncology Stakeholders to Plan Multi-site Cancer Caregiving Research (CONNECT WF-2300CD).
Sarah S Asad1, Beverly J Levine2, Anna C Snavely3
1Department of Implementation Science, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
JNCI Cancer Spectrum
|June 22, 2026
Summary
Community oncology practices show high interest in cancer caregiver clinical trials but face capacity barriers. Strategies like clear guidance and resource support are needed to improve participation.
Area of Science:
- Oncology Clinical Trials
- Community Oncology
- Health Services Research
Background:
- Engaging community stakeholders is crucial for successful clinical trial planning.
- Identifying barriers and facilitators enhances participation in oncology research.
- Caregiver involvement in clinical trials addresses a critical need in cancer care.
Purpose of the Study:
- Assess the interest and perceived capacity of National Community Oncology Research Program (NCORP) practices for a future caregiver-focused clinical trial.
- Identify barriers and facilitators to participation in multi-site caregiver clinical trials.
- Inform the design of a future clinical trial involving cancer patients and their caregivers.
Main Methods:
- A cross-sectional survey (WF-2300CD) was administered to NCORP practices.
- Assessed practice interest, capacity (accruals, implementers), and barriers/facilitators.
- Analyzed data using logistic regression and content analysis of free-text responses.
Main Results:
- 84.9% of practices expressed interest in a caregiver trial, but only 37.3% met capacity criteria.
- Practice capacity was the sole predictor of interest (adjusted OR 5.79).
- Key barriers included staffing, eligibility, and recruitment; clear guidance and resources were suggested.
Conclusions:
- Early stakeholder engagement identified actionable strategies to improve caregiver trial participation in community oncology.
- Targeted capacity-building initiatives are essential for enhancing participation in future caregiver-focused trials.
- Practice-aligned strategies can overcome identified barriers to caregiver trial accrual.
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