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Updated: Jun 24, 2026

Sexual Transmission of American Trypanosomes from Males and Females to Naive Mates

Sexual Transmission of American Trypanosomes from Males and Females to Naive Mates

Published on: January 27, 2019

Rethinking Chagas disease for 21st-century health systems.

Vibhu Kanna Rajesh Kanna¹, Sangkavi Kuhan², Faraan O Rahim³

¹The University of Texas at Austin, Austin, TX, USA.

International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases

|June 22, 2026

Summary

This summary is machine-generated.

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Chagas disease, a neglected tropical infection, is increasingly affecting older adults as a chronic cardiomyopathy. Addressing this requires reframing the disease and expanding care beyond endemic regions.

Area of Science:

Global Health
Infectious Diseases
Cardiology

Background:

Chagas disease affects 10.5 million globally, disproportionately impacting underserved populations.
While age-standardized mortality has declined, the disease burden is shifting towards older adults.
Migration is increasing Chagas disease prevalence in non-endemic Western countries with limited awareness and diagnosis.

Purpose of the Study:

To highlight priorities for addressing the evolving global burden of Chagas disease.
To advocate for a shift in perspective from a neglected tropical infection to a neglected chronic cardiomyopathy.
To emphasize the need for expanded screening and care responsibilities.

Main Methods:

Review of current epidemiological trends and disease burden.

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Analysis of the transition from acute to chronic manifestations.

Identification of key challenges in non-endemic regions.

Main Results:

Chagas disease is increasingly a chronic condition in aging populations.
Limited clinical awareness, screening, and diagnosis in Western countries pose significant challenges.
The disease burden is shifting to older adults and non-endemic regions.

Conclusions:

Reframing Chagas disease as a chronic cardiovascular condition is crucial.
Expanding screening and clinical care responsibilities beyond endemic countries is essential.
Strengthening surveillance and epidemiological data systems is vital for effective management.