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iLips^®: A 5-Years Experience with a Highly Reproducible Approach for Dynamic Lip Filler.

Marco Gratteri¹, Pierluigi Gigliofiorito^2,3, Marco Palmesano^4,5

¹Department of Plastic, Reconstructive and Cosmetic Surgery, Campus Bio-Medico University Hospital, Rome, Italy.

Aesthetic Plastic Surgery

|June 22, 2026

Summary

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The iLips technique for lip augmentation, using a cohesive filler, significantly reduces migration risks and improves aesthetic and psychological outcomes. This method ensures patient satisfaction and safety in lip enhancement procedures.

Area of Science:

Plastic Surgery
Dermatology
Aesthetic Medicine

Background:

Lip filler migration is a significant concern.
Elastic and cohesive fillers, when injected correctly, can mitigate this risk.
The iLips technique utilizes these properties for improved lip augmentation.

Purpose of the Study:

To evaluate the 5-year experience with the iLips lip filling technique.
To assess the safety, efficacy, and patient satisfaction of this novel approach.
To determine the risk of filler migration with the iLips method.

Main Methods:

A prospective study of 4583 patients using the iLips technique.
Objective aesthetic evaluation using the Lip Fullness Merz scale by external surgeons.
Patient-reported outcome measures (PROMs) assessed via FACE-Q scales.

Keywords:

Dermal filler Dynamic filler Filler migration Lip augmentation Lip filler

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Analysis of complication rates, including vascular events.

Main Results:

Significant improvement in Lip Fullness Merz scores for both upper and lower lips (p<0.05).
Positive trends in patient-reported outcomes for psychological function and satisfaction.
A low rate of major vascular complications (2 cases) was reported.

Conclusions:

The iLips technique is a safe, reproducible, and effective method for lip augmentation.
This approach enhances patient satisfaction and positively impacts psychological well-being.
The technique minimizes the risk of filler migration.