Related Experiment Video
Updated: Jun 24, 2026
Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility
Published on: May 30, 2025
The effect of glandular frenulectomy on refractory lifelong premature ejaculation: a pilot study
Mohamed Farid Roaiah1, Yasser Ibrahim El Khayat1, Omar Ayman Saad El Din1
1Department of Andrology, Sexology & STDs, Faculty of Medicine, Cairo University, Cairo.
Purpose:
Premature ejaculation (PE) is one of the most common male sexual disorders and is influenced by both psychological and biological factors. Despite available treatments, including psychosexual therapy and pharmacological interventions, no definitive cure exists. In addition, various interventional approaches have been investigated for lifelong PE, such as glandular filler injections, partial dorsal nerve neurectomy, and frenulectomy.
Patients And Methods:
This pilot study evaluated the effect of glandular frenulectomy in 25 married men with lifelong PE who had not responded to conventional treatments for at least six months. Participants underwent glandular frenulectomy and were assessed before surgery and three months postoperatively using Intravaginal Ejaculatory Latency Time (IELT) and the Arabic Index of Premature Ejaculation (AIPE) scores.
Results:
No statistically significant improvement was observed in IELT or AIPE scores after surgery. The mean IELT and AIPE scores before and three months postoperatively yielded P-values of 0.058 and 0.090, respectively.
Conclusion:
In this pilot study, glandular frenulectomy did not result in significant short-term improvement in men with lifelong PE unresponsive to conventional therapy. Larger studies with longer follow-up are needed to further evaluate its therapeutic role.
