Diffuse Gastric Uptake and Metabolic Superscan in the Patient with Multiple Myeloma

Metastatic calcification is characterized by abnormal deposition of calcium in extraosseous tissues resulting from disruption of calcium-phosphorus homeostasis. It occurs without tissue damage and is usually seen in normal organs. It is most commonly observed in patients with chronic renal failure, paraneoplastic hypercalcemia, and vitamin D intoxication. Metabolic superscan is characterized by diffusely increased skeletal activity with suppressed renal visualization, often without soft-tissue involvement. This pattern reflects altered radiotracer biodistribution secondary to severe metabolic bone turnover. We report a case of multiple myeloma in which diffuse ^99mTc-MDP uptake was observed in the stomach on a metabolic superscan.