Related Experiment Video
Updated: Jun 24, 2026

Radiotracer Administration for High Temporal Resolution Positron Emission Tomography of the Human Brain: Application to FDG-fPET
Published on: October 22, 2019
FDG: Five decades of transforming molecular imaging and still illuminating the brain
Shokouh Arjmand1,2, Paul Cumming3, Albert Gjedde2,4,5
1Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden.
Abstract:
Over half a century after its introduction, [18F]fluorodeoxyglucose ([18F]FDG) remains a cornerstone of molecular imaging by positron emission tomography (PET). This commentary reflects on [18F]FDG-PET's transformative role in neuroscience, highlighting its fundamental contributions to understanding brain metabolism and supporting clinical diagnoses of brain disorders, and the continuing evolution and refinement of brain PET imaging.
Related Concept Videos
Positron Emission Tomography
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body being...
Imaging Studies II: Positron Emission Tomography and Scintigraphy
Fundamental Principles of PET
Brain Imaging
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans), magnetic resonance imaging (MRI), functional magnetic resonance imaging (fMRI), and Transcranial Magnetic Stimulation (TMS).

![Semi-quantitative Assessment Using [18F]FDG Tracer in Patients with Severe Brain Injury](/_next/image?url=https%3A%2F%2Fcloudfront.jove.com%2FCDNSource%2Fteasers%2F58641.jpg&w=3840&q=50)