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Updated: Jun 24, 2026

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A Rehabilitation Program of Exoskeleton-assisted Body Weight-Supported Treadmill Training with Non-immersive Virtual Reality for Stroke Patients
Published on: May 16, 2025
Backward Incline Walking in Stroke Rehabilitation: A Pilot Feasibility Study.
Sharareh Sharififar1, Chris Lamprecht1, Anna Yozefovich Khanna2
1Department of Physical Medicine and Rehabilitation, College of Medicine, University of Florida, Gainesville, FL, USA.
Restorative Neurology and Neuroscience
|June 23, 2026
Summary
Backward incline walking on a treadmill is a feasible and safe rehabilitation strategy for individuals with chronic stroke. This pilot study found the protocol well-tolerated, suggesting potential for future efficacy trials in stroke recovery.
Area of Science:
- Neurology
- Rehabilitation Medicine
- Biomechanics
Background:
- Restoring normal gait function after stroke is a significant clinical challenge.
- Backward walking and incline walking increase neuromotor demands, potentially benefiting stroke rehabilitation.
- The feasibility and safety of backward incline walking in chronic stroke patients remain underexplored.
Purpose of the Study:
- To assess the feasibility, safety, and tolerability of a single-session treadmill-based backward incline walking protocol.
- To evaluate participant recruitment, adherence, safety, perceived exertion, and acceptability in individuals with chronic stroke.
Main Methods:
- A prospective, nonrandomized pilot feasibility study was conducted.
- Six individuals with chronic stroke completed three treadmill walking conditions: level, forward incline, and backward incline.
- Feasibility metrics included recruitment rate, adherence, adverse events, perceived exertion, and acceptability.
Main Results:
- The protocol demonstrated feasibility, with a 40% recruitment rate.
- All participants completed the session safely without adverse events.
- Backward incline walking resulted in the highest perceived exertion (median RPE=6) and was highly acceptable to participants.
Conclusions:
- Treadmill-based backward incline walking is a feasible, safe, and well-tolerated intervention for ambulatory individuals with chronic stroke.
- This pilot study supports progression to larger randomized trials to evaluate efficacy.
- Further research should address order effects and individualized responses to this gait training method.
