Related Experiment Video
Updated: Jun 25, 2026

Signal Acquisition, Score Interpretation, and Economics of a Non-Invasive Point-of-Care Test for Coronary Artery Disease
Published on: August 9, 2024
Prognostic Utility of the BCIS-CHIP Score in Imaging-Guided Percutaneous Coronary Intervention
Yuki Nakata1, Eiji Shibahashi1, Hisao Otsuki1
1Department of Cardiology, Tokyo Women's Medical University, Tokyo, Japan.
Insights
The British Cardiovascular Intervention Society (BCIS) complex high-risk indicated percutaneous coronary intervention (CHIP) score effectively predicts cardiovascular events in patients undergoing imaging-guided PCI, simplifying risk stratification.
Area of Science:
- Cardiology
- Interventional Cardiology
- Clinical Risk Stratification
Background:
- The British Cardiovascular Intervention Society (BCIS) developed a complex high-risk indicated percutaneous coronary intervention (CHIP) score.
- Its prognostic value is established, but validation in imaging-guided PCI is lacking.
- Imaging-guided PCI shows a favorable prognostic association with CHIP.
Purpose of the Study:
- To investigate the utility of the BCIS-CHIP score in patients undergoing imaging-guided PCI.
- To assess the prognostic value of the BCIS-CHIP score in this specific patient population.
Main Methods:
- A multicenter prospective observational study included 1218 patients undergoing imaging-guided PCI.
- Patients were stratified into four groups based on BCIS-CHIP scores (0, 1-2, 3-4, ≥5).
- The primary endpoint was 1-year major adverse cardiac or cerebrovascular events (MACCE); secondary outcomes included individual MACCE components, target vessel revascularization, and heart failure.
Main Results:
- MACCE incidence at 1 year was 1.8% (score 0), 3.4% (1-2), 7.3% (3-4), and 11.7% (≥5) (p<0.001).
- Patients with scores 3-4 (HR: 4.2) and ≥5 (HR: 7.4) had significantly higher MACCE rates compared to score 0.
- The BCIS-CHIP score demonstrated a clear gradient of risk.
Conclusions:
- The BCIS-CHIP score is a valuable tool for predicting cardiovascular events in patients undergoing imaging-guided PCI.
- It can simplify the risk stratification process for patients with CHIP undergoing this procedure.
Abstract:
A complex high-risk indicated percutaneous coronary intervention (CHIP) score was recently developed from the British Cardiovascular Intervention Society (BCIS) database, and its prognostic value has been reported. However, its utility remains nonvalidated in imaging-guided percutaneous coronary intervention (PCI), which has a favorable prognostic association with CHIP. We investigated the usefulness of the BCIS-CHIP score under imaging-guided PCI. This multicenter prospective observational study included patients who underwent imaging-guided PCI. Patients were evaluated and categorized into 4 groups based on BCIS-CHIP scores (0, 1 to 2, 3 to 4, ≥5), for which we assessed the incidence of 1-year major adverse cardiac or cerebrovascular events (MACCE), including all-cause death, nonfatal myocardial infarction, and nonfatal stroke. Secondary outcomes were individual MACCE components, target vessel revascularization, and heart failure events. In total, 1,218 patients were included. MACCE at 1 year occurred in 1.8%, 3.4%, 7.3%, and 11.7% of patients with BCIS-CHIP scores 0, 1 to 2, 3 to 4, and ≥5, respectively (p <0.001). The incidence of a primary endpoint in groups 3-4 (HR: 4.2, 95% CI: 1.48 to 12.2) and ≥5 (HR: 7.4, 95% CI: 2.59 to 21.37) was significantly higher than those in group 0. The BCIS-CHIP score is useful for predicting cardiovascular events in patients who have undergone imaging-guided PCI and could simplify risk stratification of patients with CHIP.
Related Concept Videos
Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT
Acute Coronary Syndrome III: Diagnostic Studies
Imaging Studies for Cardiovascular System V: CT
Cardiac Catheterization I: Pre-Procedure Overview