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  1. Home
  3. Cardiovascular Risks And Hazards Associated With Deep Space Exploration.
  1. Home
  3. Cardiovascular Risks And Hazards Associated With Deep Space Exploration.

Related Experiment Video

Exploring the Effects of Spaceflight on Mouse Physiology using the Open Access NASA GeneLab Platform
11:08

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Published on: January 13, 2019

Cardiovascular risks and hazards associated with deep space exploration.

Agnieszka Brojakowska1,2, Malik Bisserier3, Abrisham Eskandari1

  • 1Cardiovascular Research Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

Communications Medicine
|June 23, 2026

View abstract on PubMed

Summary
This summary is machine-generated.

Deep-space missions pose significant cardiovascular risks to astronauts due to microgravity, radiation, and isolation. This review examines potential cardiovascular disease risks during exploration-type space travel.

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Coherence between Brain Cortical Function and Neurocognitive Performance during Changed Gravity Conditions
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Coherence between Brain Cortical Function and Neurocognitive Performance during Changed Gravity Conditions

Published on: May 23, 2011

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12:29

Coherence between Brain Cortical Function and Neurocognitive Performance during Changed Gravity Conditions

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Area of Science:

  • Space medicine
  • Cardiovascular physiology
  • Astrobiology

Background:

  • Space flight presents unique environmental stressors: microgravity, ionizing radiation, isolation, and confinement.
  • Missions beyond low Earth orbit (LEO) involve prolonged exposure to hazards like high-energy and atomic number (HZE) particle radiation.
  • Distant missions increase logistical challenges, including limited medical access and supplies.

Purpose of the Study:

  • To comprehensively review the cardiovascular disease risks associated with deep-space exploration.
  • To identify potential cardiovascular challenges during and after long-duration space missions.
  • To inform future research and countermeasures for astronaut cardiovascular health.

Main Methods:

  • Literature review of existing studies on space travel and cardiovascular effects.
  • Analysis of known physiological responses to spaceflight stressors.
  • Identification of potential cardiovascular risks for deep-space missions.

    • Main Results:

    • Known space travel effects on the cardiovascular system include dysrhythmias, altered vascular compliance, dysautonomia, and inflammation.
    • The manifestation of these risks and other unknown cardiovascular issues during deep-space missions is not fully understood.
    • Prolonged exposure to radiation and microgravity may exacerbate cardiovascular conditions.

    Conclusions:

    • Deep-space exploration introduces significant and potentially unknown cardiovascular disease risks.
    • Further research is crucial to understand and mitigate these risks for astronaut safety.
    • Developing effective countermeasures is essential for enabling long-duration space missions.