Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Cancer Survival Analysis01:21

Cancer Survival Analysis

Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
Study Designs in Epidemiology01:20

Study Designs in Epidemiology

Epidemiological study designs are fundamental tools for investigating the distribution, determinants, and control of health conditions in populations. They help researchers understand the relationships between exposures and outcomes, and they broadly fall into two categories: "observational" and "experimental" studies.
Observational studies are those where the researcher does not intervene but rather observes natural variations. They include cross-sectional, cohort, and case-control studies.
Cancer Prevention02:59

Cancer Prevention

Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
Cancer Prevention02:59

Cancer Prevention

Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
Models of Health Promotion and Illness Prevention II01:18

Models of Health Promotion and Illness Prevention II

The person's health status fluctuates continually, varying from being in good health to becoming ill and returning to being healthy. To understand the concept of illness prevention, there are two models. First, the health-illness continuum model is a graphic representation of an individual's wellness. It states that a person is considered healthy in the absence of physical disease and the presence of good emotional health.
The agent-host-environment model states that disease results from...
Combination Therapies and Personalized Medicine02:50

Combination Therapies and Personalized Medicine

Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

TIME-trend and forecasting of the economic impact of inflammatory bowel disease in Catalonia: a population-based analysis.

Journal of medical economics·2026
Same author

Barriers to and facilitators of maintaining physical activity for people with hip and knee osteoarthritis: a mixed-methods systematic review.

Rheumatology international·2026
Same author

Culturally and regionally relevant physical activity for public health promotion in a global context: nature of the evidence and definition development from a narrative review.

BMJ public health·2026
Same author

Is physical activity and sport participation equal for all adolescents in Ireland?

Journal of science and medicine in sport·2026
Same author

The impact of a national transition of treatment platform on the acceptance of internet-delivered cognitive behavioral therapy: A longitudinal study among Norwegian therapists.

Internet interventions·2026
Same author

Prevalence, incidence and mortality of pediatric inflammatory bowel disease in Catalonia (EPIBDCat).

Revista espanola de enfermedades digestivas·2026

Related Experiment Videos

The PIECES multi-site comparative case study protocol: mixed methods implementation evaluation of adapting,

Nikita Hensen1,2, Rixt A Smit3,4, Anna Barrero5,6

  • 1Amsterdam UMC, Vrije Universiteit Amsterdam, Department of Public and Occupational Health, Amsterdam, The Netherlands. n.hensen@amsterdamumc.nl.

Implementation Science Communications
|June 24, 2026
PubMed
Summary

This study evaluates a toolkit designed to improve the tailored implementation of primary cancer prevention (PCP) programs. The PIECES project uses a mixed-methods approach across 11 international sites to assess the toolkit's impact on implementation competencies.

Keywords:
Healthcare implementationPrimary cancer preventionProcess evaluationProgram adaptationRealist evaluationTailoringToolkit

Related Experiment Videos

Area of Science:

  • Implementation Science
  • Public Health
  • Cancer Prevention

Background:

  • Evidence-based primary cancer prevention (PCP) programs often struggle with real-world implementation due to context-specific challenges.
  • Existing frameworks for program adaptation and tailoring lack practical guidance for operationalization.
  • The PIECES project addresses this gap by developing and evaluating structured support for tailored PCP program implementation.

Purpose of the Study:

  • To evaluate the usability, feasibility, and impact mechanisms of a co-developed toolkit designed to support tailored implementation of PCP programs.
  • To strengthen practitioners' and researchers' implementation competencies through structured planning and evidence-informed decision-making.
  • To provide practical guidance for adapting, tailoring, implementing, and evaluating PCP programs across diverse settings.

Main Methods:

  • A multi-site pre-post comparative case study design with mixed-methods implementation evaluation across 11 European and Australian sites.
  • Process evaluation guided by the UK MRC Process Evaluation Framework and Proctor's implementation outcomes, examining usability, feasibility, and satisfaction.
  • Realist evaluation to explore how, why, and under what conditions the toolkit supports tailored implementation, using quantitative and qualitative data.

Main Results:

  • The primary outcome is the change in implementation competencies among toolkit users.
  • Data collection includes quantitative and qualitative data, toolkit logs, and field notes from 2025-2027.
  • The study will provide insights into the mechanisms and contextual factors influencing tailored implementation.

Conclusions:

  • The PIECES study is expected to advance implementation science by evaluating a structured, evidence-informed tool for tailored PCP program implementation.
  • The multi-country design will explore the functioning of implementation support tools across diverse contexts.
  • Integrating process and realist evaluations aims to generate evidence for scalable, context-sensitive strategies to enhance prevention efforts.