Related Experiment Video
Updated: Jun 25, 2026

CD Spectroscopy to Study DNA-Protein Interactions
Published on: February 10, 2022
Guidelines for Comparing Circular Dichroism Spectroscopy and Molecular Dynamics Simulations for Biomolecules
Cinzia Campus1,2, Marta Roldo2, Charles H Chen3
1Department of Chemical, Physical, Mathematical and Natural Sciences, Sassari, Italy.
None:
We consider a combination of circular dichroism (CD) spectroscopy and molecular dynamics (MD) simulations to study peptide partitioning through biological membranes. We discuss the main equations involved in both methods, including their caveats and practical limitations. We then proceed to outline a set of recommendations for how to best compare CD to MD data sources, including methodological limitations. We envisage that this work can serve as a reference source for community members seeking to glean insights via a combination of CD and MD methods.
More Related Videos
08:54Vibrational Spectra of a N719-Chromophore/Titania Interface from Empirical-Potential Molecular-Dynamics Simulation, Solvated by a Room Temperature Ionic Liquid
Published on: January 25, 2020
09:15Measuring Biomolecular DSC Profiles with Thermolabile Ligands to Rapidly Characterize Folding and Binding Interactions
Published on: November 21, 2017