Related Experiment Video
Updated: Jun 25, 2026

Robust Ligature-Induced Model of Murine Periodontitis for the Evaluation of Oral Neutrophils
Published on: January 21, 2020
Atypical manifestation of necrotizing ulcerative gingivitis in a healthy patient
Prasannasrinivas Deshpande1, Karthikeya Patil1, Sathish Radhakrishna2
1Department of Oral Medicine and Radiology, JSS Dental College and Hospital, JSS Academy of Higher Education and Research, Mysore, Karnataka, India.
Abstract:
Necrotizing periodontal disease encompasses a range of conditions marked by necrosis and ulceration. Necrotizing ulcerative gingivitis is a unique type of periodontal disease that starts quickly and severely. It is caused by a number of risk factors, including stress, poor nutrition, conditions that weaken the immune system, and bad oral hygiene. The 2017 classification has redefined this condition as "necrotizing gingivitis (NG)," which clinically presents as a generalized lesion primarily in the anterior mandible, characterized by inflamed interdental papillae, gingival bleeding, necrosis, and often accompanied by pain. Recently, NG is deemed infrequent owing to the availability of diverse oral hygiene agents, potentially resulting in misdiagnosis as alternative infectious lesions. A comprehensive understanding of the disease is essential for precise diagnosis and effective treatment planning. This case illustrates a distinctive manifestation of NG in a healthy young girl who experienced this uncommon occurrence. A precise diagnostic method accompanied by a range of conservative treatment options has been provided.
Related Concept Videos
The Oral Microbiota
Endocarditis II: Clinical Features of Infective Endocarditis
Peptic Ulcer
Peptic Ulcer Disease III: Clinical Manifestations and Complications
Peptic Ulcer Disease II: Pathophysiology
Peptic Ulcer Disease II: Pathophysiology
Damaging agents such as Helicobacter pylori, gastric acid, pepsin, and nonsteroidal anti-inflammatory drugs (NSAIDs) can weaken the mucosal defense, allowing hydrogen ions to infiltrate back and harm epithelial cells.

