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Updated: Jun 25, 2026
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Endoscopic Bilateral Nipple-sparing Mastectomy via a Single Axillary Incision with Immediate Pre-pectoral Implant-based Breast Reconstruction
Published on: May 17, 2024
Autologous Versus Implant-Based Breast Reconstruction: Insights From Recent Oncologic and Plastic Surgery Guidelines
Esaúl Marroquín León1, Daniel Sanchez1, Ángel Gutiérrez Lamont2
1Medicine, Universidad Westhill, Mexico City, MEX.
Cureus
|June 24, 2026
Summary
Mastectomy reconstruction options include autologous tissue or implants. Autologous reconstruction offers better long-term quality of life, while implant-based methods have specific risks, especially with radiotherapy.
Area of Science:
- Oncology
- Plastic Surgery
- Evidence-Based Medicine
Background:
- High mastectomy rates necessitate advanced breast reconstruction techniques.
- Breast reconstruction is integral to comprehensive breast cancer care.
- Autologous and implant-based procedures are the primary reconstruction methods.
Purpose of the Study:
- To compare autologous and implant-based post-mastectomy breast reconstruction.
- To synthesize current clinical guidelines and literature on reconstruction modalities.
- To provide an evidence-based comparison considering oncological, surgical, and patient factors.
Main Methods:
- Comprehensive literature search for clinical guidelines and high-quality studies.
- Evaluation of radiotherapy effects, complication rates, and patient-reported outcome measures (PROMs) using BREAST-Q.
- Comparison of prepectoral implants versus autologous reconstruction outcomes.
Main Results:
- Prepectoral implants reduce pain and animation deformity but increase seroma rates and risk of failure with radiotherapy.
- Autologous reconstruction demonstrates superior long-term psychosocial and sexual quality of life.
- Obesity and smoking are key factors influencing reconstructive success and failure rates.
Conclusions:
- The choice between autologous and implant-based reconstruction depends on oncological needs, surgical risks, and patient preferences.
- Autologous reconstruction is associated with better long-term outcomes for psychosocial and sexual well-being.
- Patient factors like obesity and smoking status significantly impact reconstructive outcomes.
