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Related Experiment Video

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Short Session High Intensity Interval Training and Treadmill Assessment in Aged Mice
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Cycle-based high-intensity sprint exercise elicits acute cognitive dysfunction in psychomotor and memory task

Trevor J Dufner1, Jessica M Moon1, Adam J Wells1

  • 1Exercise Physiology Intervention and Collaboration Laboratory, Institute of Exercise Physiology and Rehabilitation Science, University of Central Florida, Orlando, FL, United States.

Frontiers in Cognition
|June 24, 2026
PubMed
Summary
This summary is machine-generated.

High-intensity sprint exercise temporarily impairs cognitive function, specifically in psychomotor and memory tasks. This effect highlights the impact of intense exercise on cognitive performance shortly after completion.

Keywords:
ANAMDynavisionattentioncognitioncognitive dysfunctionhigh-intensity sprint exercisememory

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Area of Science:

  • Exercise Physiology
  • Cognitive Neuroscience
  • Sports Science

Background:

  • High-intensity exercise protocols are increasingly studied for their physiological effects.
  • Understanding the impact of acute exercise on cognitive function is crucial for athletes and general populations.
  • Previous research has yielded mixed results regarding exercise-induced cognitive changes.

Purpose of the Study:

  • To investigate the effects of a high-intensity sprint exercise protocol (HISEP) on cognitive function.
  • To assess changes in psychomotor, attentional, executive, and memory tasks following HISEP.
  • To determine the feasibility of HISEP as a tool for inducing temporary cognitive dysfunction.

Main Methods:

  • Twenty-four recreationally active adults participated in the study.
  • Participants completed a HISEP on a cycle ergometer.
  • Cognitive performance, psychomotor reaction time, and mood were assessed pre-, immediately post-, and 60-minutes post-exercise.

Main Results:

  • Fatigue significantly increased immediately post-exercise.
  • Psychomotor reaction time (Mode A) was slower immediately post-exercise.
  • Cognitive performance, specifically in code substitution-delayed and matching to sample tasks, showed reduced throughput post-exercise.
  • Mathematical processing performance improved 60 minutes post-exercise.

Conclusions:

  • High-intensity sprint exercise protocol is an effective and time-efficient method to induce acute cognitive dysfunction.
  • The observed cognitive impairments were primarily in psychomotor and memory-related tasks.
  • These findings suggest a temporary negative impact of intense exercise on specific cognitive domains.