Related Experiment Video
Updated: Jun 25, 2026

Improving IV Insulin Administration in a Community Hospital
Published on: June 11, 2012
Automated Insulin Delivery: Great Strides in the Past, Great Needs for the Future
Rachel Seese1, Charlotte Katie Boughton1,2, Roman Hovorka1
1Institute of Metabolic Science-Metabolic Research Laboratories, University of Cambridge, Cambridge, U.K.
Abstract:
Advances in diabetes technologies are transforming the management of type 1 diabetes. In this review, we reflect on the successful translation from bench to bedside of hybrid automated insulin delivery (AID) systems, including development of the core components as well as commercialization, and then we focus on progress toward next-generation fully automated systems. With the availability of greater choice, we review the factors that influence users and health care professionals when selecting an AID system while recognizing the challenges of comparing AID systems. We discuss the importance of the diabetes technology ecosystem in ensuring equity of access and effective implementation. We contrast the different potential approaches to fully automated systems that could reduce burden, including the use of ultrarapid insulins, adjunctive therapies, integration of signals from additional wearables, and dual-hormone systems. Finally, we review emerging evidence for the use of AID in more vulnerable people with type 1 diabetes, in adults with type 2 diabetes, in people with cystic fibrosis-related diabetes, and in the inpatient setting.
Related Concept Videos
Insulin Formulations: Types and Delivery
Short-acting insulins are divided into rapid-acting...
Parenteral Drug Delivery Systems: Injectables, Implants, and Infusion Devices
Insulin: Dosing Regimen and Adverse Effects
The basal dose constitutes about 40%-50% of the total daily dose, with the rest as premeal insulin. The mealtime insulin dose should mirror...
Insulin: Biosynthesis, Chemistry, and Preparation
Damage or functional impairment of β-cells inhibits insulin production, leading to diabetes. Diabetes treatment primarily uses...
Issues And Trends In Healthcare Delivery System
Cost Containment
Payment for healthcare services has historically promoted adoption of costly and often unnecessary or inefficient...
Production of Pharmaceuticals

