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Machine Learning-Enabled In Situ Diagnostics for Intelligent Plasma-Based Semiconductor Manufacturing: A Review.
Minji Kang1,2, Seongho Kim1,2, Eunseo Go1,2
1Semiconductor Manufacturing Research Center, Korea Institute of Machinery & Materials (KIMM), Daejeon 34103, Republic of Korea.
ACS Applied Materials & Interfaces
|June 24, 2026
Summary
Machine learning (ML) enhances semiconductor manufacturing by providing intelligent diagnostics for plasma processes. This technology enables real-time decision-making, process optimization, and fault detection, paving the way for autonomous manufacturing.
Area of Science:
- Materials Science
- Chemical Engineering
- Computer Science
Background:
- Semiconductor manufacturing complexity and tighter process tolerances necessitate advanced control strategies.
- Traditional experience-driven methods are insufficient for modern plasma-based processes.
- Machine learning (ML) offers a powerful approach to interpret complex plasma diagnostics.
Purpose of the Study:
- To review recent advancements in ML for intelligent diagnostics in plasma-based semiconductor manufacturing.
- To analyze ML applications from both equipment and ML-focused perspectives.
- To identify challenges and propose future directions for AI in plasma processing.
Main Methods:
- Review of recent studies on ML applications in plasma-enhanced chemical vapor deposition, reactive ion etching, and sputtering.
- Classification of ML applications including anomaly detection, plasma diagnostics, and predictive maintenance.
- Examination of emerging strategies like physics-informed learning and explainable AI.
Main Results:
- ML models successfully capture nonlinear plasma behavior and enable virtual metrology.
- ML facilitates early fault detection, process optimization, and noninvasive monitoring.
- Significant progress has been made in real-time data analysis and in situ diagnostics.
Conclusions:
- ML is transforming semiconductor plasma processing, enabling intelligent diagnostics and real-time decision-making.
- Barriers such as data availability and model interpretability need addressing.
- Emerging strategies and a technological roadmap are crucial for industrial readiness and autonomous manufacturing.

