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Feasibility of dl-DECT for Postmortem Interval Estimation Through Changes in Yellow Bone Marrow: Preliminary Results
Vincenzo Cianci1, Marco Cavallaro2, Simone Barbera2
1Department of Biomedical and Dental Sciences and Morphofunctional Imaging, Section of Legal Medicine, University of Messina, Messina, Italy.
La Clinica Terapeutica
|June 24, 2026
Summary
Estimating time of death is difficult in forensic pathology. This study explores yellow bone marrow analysis using dual-layer dual-energy computed tomography (dl-DECT) as a novel method for improving post-mortem interval estimations.
Area of Science:
- Forensic Pathology
- Radiology
- Biomedical Imaging
Background:
- Accurate post-mortem interval estimation is crucial in forensic investigations.
- Current methods for determining time of death are often unreliable due to various influencing factors.
Purpose of the Study:
- To introduce an innovative method for refining post-mortem interval estimations.
- To investigate the potential of analyzing yellow bone marrow composition for time of death determination.
Main Methods:
- Utilizing dual-layer dual-energy computed tomography (dl-DECT) to analyze yellow bone marrow.
- Examining cadaveric femurs for post-mortem alterations in bone marrow composition.
Main Results:
- Observed fluid-like components in the yellow bone marrow of cadaveric femurs.
- These findings suggest potential post-mortem changes within the bone marrow.
Conclusions:
- The presence of fluid-like components in yellow bone marrow may indicate post-mortem phenomena.
- Preliminary results suggest dl-DECT is a promising tool for post-mortem interval estimation.
- Further research is needed to correlate bone marrow water variations with the time since death.

