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The Infinite Choices of Local (Re)-Treatment for Oligometastatic Breast Cancer: Angst, Leap of Faith, or a Safe Bet?

Francesco Dionisi1, Giuseppe Sanguineti1

  • 1Department of Research and Advanced Technology, IRCCS Regina Elena National Cancer Institute, Rome, Italy.

International Journal of Radiation Oncology, Biology, Physics
|June 24, 2026
PubMed
Abstract

No abstract available in PubMed .

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Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
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Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...

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