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Updated: Jun 26, 2026

Manufacture and Drug Delivery Applications of Silk Nanoparticles
Published on: October 8, 2016
Recent advances in nanomedicine as drug delivery system
Minh-Dat Quoc Tang1, Bao-Nhien Au1, Van Khanh Hoang1
1School of Biomedical Engineering, International University, Ho Chi Minh, Vietnam; Vietnam National University Ho Chi Minh City (VNU-HCM), Ho Chi Minh, Vietnam.
Abstract:
The development and application of nanoscale materials for tackling medical and health-related challenges is garnering considerable interest. By loading or attaching small molecule drugs in structure, these nanocarriers can improve the pharmacokinetic profile, toxicity, and therapeutic efficacy of cargos. This leads to unique advantages of nanomedicine in clinical results in comparison with conventional drugs. Nevertheless, numerous nanotherapeutics fail to prevent harm to healthy tissues due to their lack of specific accumulation and controlled drug release in disease sites. In this review, we briefly describe some common types of nanoparticles as drug delivery systems and present advanced approaches to improve circulation time and site-specific accumulation of nanoparticles. Then, the strategies for controlled drug release from nanocarriers upon differential internal and external stimulations are also discussed followed by the introduction of recently approval nanomedicines.
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