Related Experiment Video
Updated: Jun 26, 2026

Corneal Epithelial Abrasion with Ocular Burr As a Model for Cornea Wound Healing
Published on: July 10, 2018
Topical Anesthetics for Simple Corneal Abrasions
1Department of Emergency Medicine, Old Dominion University, Raleigh Building #304, 600 Gresham Drive, Norfolk, VA 23507, USA.
Abstract:
Corneal abrasions are some of the most common ocular complaints seen in the emergency department and are associated with significant discomfort. Although simple corneal abrasions usually heal within 2 to 3 days, treatment is often needed to help alleviate the pain. The prescribing of topical anesthetics historically has been strongly discouraged due to concerns for complications such as corneal melting and scaring. Here, we review the evidence behind this long-standing concern and propose a potentially safe role for short-term topical anesthetic use.
Related Concept Videos
Local Anesthetics: Common Agents and Their Applications
Cocaine is an ester of benzoic acid and methylecgogine. It is used to anesthetize and vasoconstrict locally. Currently, it is used primarily for topical applications. It is beneficial for surgeries on the upper respiratory tract, providing anesthesia and shrinking the mucosa. Cocaine in the form of cocaine hydrochloride is...
Local Anesthetics: Clinical Application as Surface, Infiltration, and Conduction Block Anesthesia
Ophthalmic Drug Delivery Systems
Local Anesthetics: Chemistry and Structure-Activity Relationship

