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Updated: Jun 26, 2026
Robot-assisted Total Mesorectal Excision and Lateral Pelvic Lymph Node Dissection for Locally Advanced Middle-low Rectal Cancer
Published on: February 12, 2022
[Discussion on treatment strategies for locally recurrent rectal cancer aiming at R0 resection and pathological
1Department of General Surgery (Colorectal surgery), the Sixth Affiliated Hospital, Sun Yat-sen University,Guangzhou 510655,China Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, the Sixth Affiliated Hospital, Sun Yat-sen University,Guangzhou 510655,China Biomedical Innovation Center, the Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou 510760,China.
Abstract:
With the implementation of surgical techniques, such as total pelvic exenteration, and improvements in perioperative management, an increasing number of patients with locally recurrent rectal cancer (LRRC) are potential targets for curative surgery. Negative pathological margins (R0 resection) and favorable pathological complete response (pCR) have been identified as independent predictors of better oncological outcomes in LRRC. However, achieving R0 resection and optimal tumor regression remain primary concerns and significant challenges for colorectal surgeons. Based on the latest research both domestically and internationally, along with the clinical experience of authors' team, this article provides an overview to enhance the likelihood of achieving R0 resection and pCR from surgical strategies and perioperative therapies, aiming to offer a reference for colorectal surgeons specializing in locally recurrent rectal cancer.
