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Updated: Jun 26, 2026
07:24
Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis
Published on: February 6, 2021
Endoscope-assisted vitrectomy using a 25-gauge system for endophthalmitis: a case series
Mitsuru Otsubo1, Shun Konno2, Ami Konno2
1Department of Ophthalmology, Asahikawa Medical University, 2-1-1-1 Midorigaoka Higashi, Asahikawa, Hokkaido, 078-8510, Japan. kyokui090061@gmail.com.
BMC Ophthalmology
|June 25, 2026
Summary
Endoscope-assisted vitrectomy improved vision in seven patients with postoperative endophthalmitis. This technique offers a viable surgical option for managing this serious ocular infection.
Area of Science:
- Ophthalmology
- Surgical Innovation
- Infectious Disease Management
Background:
- Postoperative endophthalmitis is a severe intraocular infection following eye surgery.
- Prompt and effective management is crucial to preserve visual function.
- Traditional treatment may face challenges in visualizing and treating infection in the posterior segment.
Purpose of the Study:
- To evaluate the efficacy and outcomes of 25-gauge endoscope-assisted vitrectomy in managing postoperative endophthalmitis.
- To describe the surgical technique employed in these cases.
- To assess the visual acuity changes before and after the intervention.
Main Methods:
- A series of seven consecutive cases of postoperative endophthalmitis were treated.
- 25-gauge endoscope-assisted vitrectomy was performed using a 10,000-pixel endoscope.
- Anesthesia (sub-Tenon's or retrobulbar) was chosen based on pain severity.
- Best-corrected visual acuity (BCVA) was compared preoperatively and at the final visit.
Main Results:
- All seven patients experienced improved visual acuity after surgery.
- Mean final BCVA was logMAR 0.36 ± 0.35 (p=0.022).
- Successful peripheral vitreous shaving was achieved in all cases without scleral indentation.
Conclusions:
- Endoscope-assisted vitrectomy is a promising surgical approach for postoperative endophthalmitis.
- The technique allows for effective visualization and treatment of infection within the vitreous cavity.
- Further studies are warranted to confirm these findings in larger cohorts.
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