Related Experiment Video
Updated: Jun 26, 2026

Building Up Skin Models for Numerous Applications - from Two-Dimensional (2D) Monoculture to Three-Dimensional (3D) Multiculture
Published on: October 20, 2023
Aspects of Adverse Effects of Cosmetic Products: An Invited Narrative Review
1Kuchnir Dermatology and Dermatologic Surgery, Marlborough, MA, USA.
Abstract:
The use of cosmetic products is ubiquitous around the world. This article reviews the medical literature documenting adverse effects associated with cosmetic product use. An extensive, nonexhaustive literature search was conducted using the PubMed database. Studies reporting adverse effects from cosmetic products were included, encompassing case reports, case series, clinical trials and epidemiological studies. Contact dermatitis is the most common adverse effect associated with cosmetic use, affecting approximately 1-5% of the general population. Additional effects, including respiratory sensitization, photosensitization, workplace exposures and issues specific to pregnancy/lactation, are discussed. The clinical significance of these effects remains poorly understood, particularly regarding long-term exposure and cumulative health impacts. Cosmetic usage can result in a spectrum of adverse effects that represent significant clinical and public health concerns.
Related Concept Videos
Effects of Chemicals: Overview
Pharmacovigilance
This process, termed pharmacovigilance, aims to detect, evaluate, and minimize harmful effects related to medication use. The data collection for pharmacovigilance depends on spontaneous reporting systems, where healthcare professionals or patients voluntarily report suspected ADRs.
In some cases, there...
Local Anesthetics: Adverse Effects
Once absorbed into the systemic circulation, local anesthetics can affect the organs that depend on the functioning of sodium...
Toxic Reactions: Overview
Toxicity falls into two primary categories: local and systemic.
Local toxicity appears at the exposure site, such as protein denaturation caused by caustic substances.
In contrast, systemic toxicity requires the toxic agent's absorption and distribution,...
Changes in Skin Color: Clinical Perspectives
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
Drug Toxicity: Overview