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Updated: Jun 26, 2026

Double-stranded RNA Oral Delivery Methods to Induce RNA Interference in Phloem and Plant-sap-feeding Hemipteran Insects
Published on: May 4, 2018
[Research advances in the biosynthesis and delivery of RNAi-based biopesticides]
Jialing Zhang1, Wenjing Duan1, Meng Sun1
1Institute of Microbiology, Heilongjiang Academy of Sciences, Harbin 150010, Heilongjiang, China.
Abstract:
RNA interference (RNAi) is a specific post-transcriptional gene silencing mechanism in eukaryotes that mediates homologous mRNA degradation based on double-stranded RNA (dsRNA). Against the backdrop of exploring and innovating green bio-agriculture, the development of environmentally friendly and reliable biopesticides has become a new trend in plant disease control. At present, RNAi-based biopesticides, as a new type of pesticides, have become a current research hotspot and a priority of development due to their strong specificity and environmental friendliness that distinguish them from chemical pesticides. This paper reviews the biosynthesis system of dsRNA and various drug delivery routes for maintaining the stability of dsRNA, with the aim of providing references for domestic research in related fields.
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