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Updated: Jun 26, 2026

Isolation of Neonatal Extrahepatic Cholangiocytes
Published on: June 5, 2014
The Latest on Intrahepatic Cholestasis of Pregnancy - Update 2026
Stanisƚaw Jurk1, Andreas Kremer2, Ekkehard Schleussner3
1Geburtshilfe und PränataldiagnostikSt. Elisabeth-Krankenhaus LeipzigLeipzigGermany.
None:
Intrahepatic cholestasis of pregnancy (ICP) is the most common liver disorder specific to pregnancy. The condition is characterised by raised serum bile acids and aminotransferases and typically presents with pruritus as its defining symptom. Ursodeoxycholic acid remains the first line therapeutic option. Clinical management - including decisions regarding the timing of delivery - is guided principally by serum bile acid concentrations, with the aim of reducing perinatal complications. This review offers a clear and integrated overview of current diagnostic criteria, management strategies, and the evidence underpinning contemporary therapeutic recommendations.
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