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Elevated D LCO and pulmonary function evolution during treatment in a patient with hyperleukocytosis and leukostasis

Santiago C Arce1, Paula M Monti1, Verónica B Cortés Guerrieri1

  • 1Instituto de Investigaciones Médicas Alfredo Lanari, Universidad de Buenos Aires, Buenos Aires, Argentina.

Breathe (Sheffield, England)
|June 25, 2026
PubMed

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Disorders of Leukocytes

Leukocyte disorders can lead to either leukopenia, characterized by an abnormally low leukocyte count, or leukocytosis, marked by a very high leukocyte number.
Leukopenia may result from bone marrow disorders, autoimmune diseases, and infectious diseases. For example, conditions such as multiple myeloma and aplastic anemia can impair the bone marrow's ability to produce adequate leukocytes. Similarly, autoimmune diseases like lupus and viral infections such as HIV can prompt the immune system...