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Published on: November 14, 2025
Perplexing Case of IgG4-Related Mastitis: Hitherto Undescribed Contrast-Enhanced Mammography Features
Veenu Singla1, Dollphy Garg1, Debajyoti Chatterjee2
1Department of Radiodiagnosis and Imaging, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
The Indian Journal of Radiology & Imaging
|June 25, 2026
Summary
Immunoglobulin G4-related mastitis (IgG4-RM) is a rare breast condition often mistaken for cancer. This case highlights its unique imaging features on contrast-enhanced mammography and FDG-PET/CT, aiding diagnosis and treatment.
Area of Science:
- Radiology
- Immunology
- Pathology
Background:
- Immunoglobulin G4-related mastitis (IgG4-RM) is a rare manifestation of IgG4-related disease (IgG4-RD).
- Breast involvement in IgG4-RD is uncommon and can mimic breast cancer, posing diagnostic challenges.
- Accurate diagnosis is crucial for appropriate management and avoiding unnecessary oncologic treatments.
