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Substance Use Disorders Affecting Sleep01:24

Substance Use Disorders Affecting Sleep

Substance use disorders involve a pattern of using drugs more extensively than intended and continuing use despite harmful consequences. This includes legal substances like alcohol and nicotine, as well as illegal drugs. These disorders often involve both physical and psychological dependence, reflecting compulsive use of substances that significantly alter thoughts, feelings, and behaviors, contributing to a major public health issue.
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The sleep cycle, an integral part of human health, consists of several stages with distinct characteristics and functions. It begins with a transition from wakefulness to sleep, known as the light sleep phase, followed by the restorative deep sleep phase, essential for physical recovery and growth. The cycle concludes with the Rapid Eye Movement (REM) phase, characterized by high brain activity and vivid dreaming. Insomnia, a prevalent sleep disorder, involves difficulty falling asleep, staying...
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Insufficient Sleep and Sleep Deprivation01:13

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Related Experiment Video

Updated: Jun 26, 2026

Human Circadian Phenotyping and Diurnal Performance Testing in the Real World
10:16

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Published on: April 7, 2020

Night-to-Night Sleep Variability Modulates Subjective Sleep Perception in Chronic Insomnia: A Multilevel Analysis.

Xiaoyu Xiao1, Shuo Liu1, Wenjing Jiang1

  • 1Department of Geriatric Medicine & Laboratory of Gerontology and Anti-Aging Research, Qilu Hospital of Shandong University, Jinan, Shandong Province, People's Republic of China.

Nature and Science of Sleep
|June 25, 2026
PubMed
Summary
This summary is machine-generated.

In chronic insomnia, daily sleep fluctuations and longer-term variability significantly impact how individuals perceive their sleep. Subjective sleep perception is less responsive to nightly objective changes in patients with insomnia.

Keywords:
intraindividual variabilitynight-to-night variabilitysleep perception biassleep state misperceptionsubjective sleep perception

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Area of Science:

  • Sleep science
  • Chronobiology
  • Clinical psychology

Background:

  • Subjective sleep perception frequently diverges from objective sleep metrics in chronic insomnia.
  • The influence of night-to-night sleep variability on this discrepancy is not well understood.

Purpose of the Study:

  • To investigate how daily within-individual sleep fluctuations and between-individual sleep variability affect subjective sleep perception in chronic insomnia patients.

Main Methods:

  • Fifty chronic insomnia patients underwent home sleep monitoring and sleep diaries for 5-7 nights.
  • Sleep perception bias was calculated as the difference between objective and subjective sleep estimates.
  • Linear mixed-effects models analyzed within-individual and between-individual variability effects.

Main Results:

  • Nightly objective sleep changes (total sleep time, efficiency, wake after sleep onset, sleep onset latency) correlated with subjective-objective discrepancies.
  • Subjective perception showed reduced responsiveness to objective nightly sleep variations.
  • Lower total sleep time variability was linked to greater bias in perceived sleep duration and efficiency.

Conclusions:

  • Subjective sleep perception in chronic insomnia is shaped by both nightly objective sleep changes and longer-term sleep variability.
  • Findings highlight the complex interplay between objective sleep patterns and subjective experience in insomnia.