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Updated: Jun 26, 2026
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Single-stage Dynamic Reanimation of the Smile in Irreversible Facial Paralysis by Free Functional Muscle Transfer
Published on: March 1, 2015
Facial Adipostructuring With Biochemical Modulation in Chronic Peripheral Facial Paralysis: A Case Report.
Hector Calfin1, Veronica Riquelme2, Gladys Velazco3,4
1Aesthetic Medicine, Climedent Puerto Montt, Puerto Montt, CHL.
Cureus
|June 25, 2026
Summary
Facial Adipostructuring (AEF) combined with biochemical modulation offers a novel, minimally invasive treatment for chronic peripheral facial paralysis (CPFP). This regenerative approach improved function from House-Brackmann grade IV to I, sustained for nine months.
Area of Science:
- Regenerative Medicine
- Facial Plastic Surgery
- Dermatology
Background:
- Chronic peripheral facial paralysis (CPFP) presents significant challenges due to lack of spontaneous recovery and limited therapeutic options.
- Conventional treatments like botulinum toxin and surgical reanimation do not address underlying structural collapse or dermal white adipose tissue (dWAT) dysfunction.
- The House-Brackmann (HB) scale grades facial nerve function, with CPFP often resulting in severe impairment (grades IV-VI).
