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Rare adverse root development after regenerative endodontic procedures: two case reports and contributing factors
Huasheng Xu1, Lu Liu2, Beibei Xie2
1Stomatology Department, Minzu Hospital of Guangxi Zhuang Autonomous Region, Nanning, China.
Frontiers in Oral Health
|June 25, 2026
Summary
Regenerative endodontic procedures (REPs) can lead to unusual root development in immature teeth, even when successful. Awareness is crucial for clinicians managing complex cases involving infection or trauma.
Area of Science:
- Dentistry
- Regenerative Endodontics
- Pediatric Dentistry
Background:
- Regenerative endodontic procedures (REPs) aim to restore immature teeth with pulp necrosis.
- Infection and trauma can cause abnormal root formation during tooth development.
- Dens evaginatus is a developmental anomaly that can lead to periapical disease.
