Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Imaging Studies I: CT and MRI

Imaging Studies I: CT and MRI

Introduction: MRI and CT scans are crucial advancements in medical imaging techniques, playing a vital role in diagnosing conditions related to the gastrointestinal (GI) system. Each scan serves distinct purposes, targets specific areas, and requires unique nursing duties.
Description of the Procedures
Computed Tomography (CT) scan:
Computed Tomography (CT) scans use X-ray technology to generate detailed images of bones, organs, and tissues. During the scan, the patient lies on a moving table...

Imaging Studies for Cardiovascular System IV: CMRI

Imaging Studies for Cardiovascular System IV: CMRI

Cardiovascular magnetic resonance imaging, or CMRI, is a non-invasive diagnostic test that employs a magnetic field and radiofrequency waves to create precise images of the heart and arteries. It provides comprehensive information about cardiac anatomy, function, perfusion, and tissue characterization without ionizing radiation.IndicationsCMRI diagnoses various heart conditions, including tissue damage from heart attacks, ischemic heart disease, myocarditis, aortic issues (tears, aneurysms,...

Imaging Studies IV: Magnetic Resonance Imaging

Imaging Studies IV: Magnetic Resonance Imaging

Introduction:Magnetic Resonance Imaging, or MRI, can include a specialized imaging technique of the urinary system known as Magnetic Resonance Urography (MRU). This radiation-free technique uses strong magnetic fields and radio waves to produce detailed images with the help of a computer. MRU is particularly effective for visualizing fluid-filled structures like the kidneys, ureters, and bladder.Applications of MRI in the Genitourinary SystemKidneys and Ureters: MRI detects tumors, cysts,...

Imaging Studies II: Positron Emission Tomography and Scintigraphy

Imaging Studies II: Positron Emission Tomography and Scintigraphy

Positron Emission Tomography (PET) is a medical imaging technique that provides crucial insights into the body's physiological functions at a molecular level. It is an indispensable resource for diagnosing, staging, and monitoring various illnesses, notably cancer, neurological disorders, and cardiovascular conditions.
Fundamental Principles of PET

Imaging Studies III: Computed Tomography

Imaging Studies III: Computed Tomography

DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Estimating fMRI timescale maps.

Imaging neuroscience (Cambridge, Mass.)·2026

Same author

Conditional and marginal SNP-heritability to leverage ancestral and environmental diversity.

bioRxiv : the preprint server for biology·2026

Same author

Estimating the fraction of variance of crystallized intelligence explained by cortical surface area in early adolescence.

bioRxiv : the preprint server for biology·2026

Same author

Quantifying uncertainty in drift diffusion models of decision making under temporal dependence and parameter variability.

bioRxiv : the preprint server for biology·2026

Same author

When can whole-genome SNP heritability be reliably estimated from summary statistics?

bioRxiv : the preprint server for biology·2026

Same author

Androgen Deprivation Therapy (ADT) and Radiotherapy (RT) with Imaging Evaluation Longitudinally (ARIEL) trial: protocol, early results, and implications of neoadjuvant ADT for focal RT boost in prostate cancer.

medRxiv : the preprint server for health sciences·2026

Search research articles

Related Experiment Video

Updated: Jun 26, 2026

Using Informational Connectivity to Measure the Synchronous Emergence of fMRI Multi-voxel Information Across Time

Using Informational Connectivity to Measure the Synchronous Emergence of fMRI Multi-voxel Information Across Time

Published on: July 1, 2014

Simultaneous confidence regions for image excursion sets: A validation study with applications in fMRI.

Jiyue Qin¹, Samuel Davenport¹, Armin Schwartzman^1,2

¹Division of Biostatistics and Bioinformatics, Herbert Wertheim School of Public Health and Human Longevity Science, University of California, San Diego, CA, United States.

Imaging Neuroscience (Cambridge, Mass.)

|June 25, 2026

Summary

This summary is machine-generated.

This study introduces a new method for simultaneous confidence regions (SCRs) in functional Magnetic Resonance Imaging (fMRI) analysis. This approach works for all activation thresholds and brain data types, improving brain activation localization.

Keywords:

bootstrap fMRI simultaneous confidence band simultaneous confidence regions

More Related Videos

Dynamic Inter-subject Functional Connectivity Reveals Moment-to-Moment Brain Network Configurations Driven by Continuous or Communication Paradigms

Dynamic Inter-subject Functional Connectivity Reveals Moment-to-Moment Brain Network Configurations Driven by Continuous or Communication Paradigms

Published on: March 21, 2019

Concurrent EEG and Functional MRI Recording and Integration Analysis for Dynamic Cortical Activity Imaging

Concurrent EEG and Functional MRI Recording and Integration Analysis for Dynamic Cortical Activity Imaging

Published on: June 30, 2018

Related Experiment Videos

Last Updated: Jun 26, 2026

Using Informational Connectivity to Measure the Synchronous Emergence of fMRI Multi-voxel Information Across Time

Using Informational Connectivity to Measure the Synchronous Emergence of fMRI Multi-voxel Information Across Time

Published on: July 1, 2014

Dynamic Inter-subject Functional Connectivity Reveals Moment-to-Moment Brain Network Configurations Driven by Continuous or Communication Paradigms

Dynamic Inter-subject Functional Connectivity Reveals Moment-to-Moment Brain Network Configurations Driven by Continuous or Communication Paradigms

Published on: March 21, 2019

Concurrent EEG and Functional MRI Recording and Integration Analysis for Dynamic Cortical Activity Imaging

Concurrent EEG and Functional MRI Recording and Integration Analysis for Dynamic Cortical Activity Imaging

Published on: June 30, 2018

Area of Science:

Neuroimaging
Statistical analysis
Brain mapping

Background:

Functional Magnetic Resonance Imaging (fMRI) is crucial for localizing brain activity during tasks.
Existing methods for confidence regions in fMRI are limited to single thresholds and brain volumes, neglecting cortical surface analyses.
There is a need for more flexible and sensitive statistical approaches in fMRI data analysis.

Purpose of the Study:

To develop and validate a novel approach for constructing simultaneous confidence regions (SCRs) applicable to all activation thresholds.
To extend existing SCR methods to handle both brain volume and cortical surface data in fMRI studies.
To evaluate the performance of different bootstrap variants for fMRI data analysis.

Main Methods:

The study adapts a bootstrap-based method for constructing simultaneous confidence bands (SCBs) to fMRI data.
Extensive 2D simulations were performed to assess the validity of various bootstrap methods, including nonparametric and multiplier bootstrap variants.
Realistic noise simulations using resampled resting-state 3D fMRI data were employed for further validation.

Main Results:

The Rademacher multiplier bootstrap-t demonstrated superior performance, achieving near-nominal coverage rates even with small sample sizes (n=10).
The proposed SCR approach is valid across all activation thresholds and applicable to both volumetric and surface-based fMRI data.
The implementation supports multi-dimensional data and includes interactive visualization tools for fMRI analysis.

Conclusions:

The developed SCR method offers a robust and versatile tool for statistical inference in fMRI studies.
This approach enhances the sensitivity and applicability of brain activation localization compared to traditional methods.
The method is validated for both simulated and real-world fMRI data, including Human Connectome Project datasets.