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Lichen Sclerosus: A Common but Often Overlooked Condition in Pediatric Patients

Begüm Avcı1, Gönül Parmaksız1, Hasan Özkan Gezer2

  • 1Department of Pediatric Nephrology, Baskent University, Adana Dr. Turgut Noyan Application and Research Center, Türkiye.

Clinical Pediatrics
|June 25, 2026
PubMed

Insights

Lichen sclerosus (LS) is often missed in children with urinary issues. Early diagnosis and treatment with topical pimecrolimus can effectively resolve symptoms and improve skin lesions in pediatric patients.

Area of Science:

  • Pediatric Nephrology
  • Dermatology

Background:

  • Lichen sclerosus (LS) is a chronic inflammatory skin condition.
  • It is frequently underdiagnosed in pediatric patients, particularly girls with urinary symptoms.

Purpose of the Study:

  • To characterize clinical features and treatment outcomes of pediatric LS presenting with urinary symptoms.
  • To raise awareness for early diagnosis and avoid unnecessary investigations.

Main Methods:

  • Retrospective study of 88 children diagnosed with LS at a pediatric nephrology center.
  • Diagnosis based on clinical and dermatoscopic findings.
  • Evaluation of treatment outcomes with topical pimecrolimus.

Main Results:

  • Mean age at diagnosis was 6.0 years, with a median delay of 8 months.
  • Dysuria and pyuria were common, but confirmed urinary tract infections were present in only 45.5%.
  • Topical pimecrolimus resolved symptoms in 88.3% and improved skin lesions in 66.6% of followed patients.

Conclusions:

  • Lichen sclerosus should be considered in the differential diagnosis for children with urinary symptoms.
  • Clinical awareness and prompt diagnosis are crucial for effective management and preventing unnecessary workups.

Keywords:
childrendysuriaincontinencelichen sclerosusurinary tract infection

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