Availability of mechanical circulatory support (MCS) and hospital survival in ST-segment elevation myocardial

Karl Heinrich Scholz1,2,3, Florian Weiser4, Tim Friede4

  • 1Department of Cardiology and Intensive Care, St. Bernward Hospital, Hildesheim, Germany.

Insights

Mechanical circulatory support (MCS) availability did not impact hospital survival for ST-elevation myocardial infarction with cardiogenic shock (STEMI-CS) patients. Outcomes were similar in centers with and without MCS, suggesting no survival benefit from MCS availability in this population.

Area of Science:

  • Cardiology
  • Interventional Cardiology
  • Critical Care Medicine

Background:

  • ST-elevation myocardial infarction with cardiogenic shock (STEMI-CS) is a severe condition where mechanical circulatory support (MCS) may improve survival.
  • It remains unclear whether centers with MCS availability offer better outcomes for STEMI-CS patients compared to those without.

Purpose of the Study:

  • To investigate the association between MCS availability and prognosis in STEMI-CS patients.
  • To compare hospital mortality rates in STEMI-CS patients treated in centers with and without MCS.

Main Methods:

  • Secondary analysis of the prospective FITT-STEMI registry.
  • Comparison of hospital mortality between STEMI-CS patients treated in MCS centers versus non-MCS centers.
  • Statistical analysis including multivariable adjustment and propensity score matching.

Main Results:

  • A total of 5604 STEMI-CS patients were analyzed (2013-2022).
  • Hospital mortality was 44.7% in MCS centers and 45.0% in non-MCS centers (OR 0.985, p=0.820), with no significant difference after adjustments or matching.
  • Patients in MCS centers were younger and less frequently resuscitated, but had longer contact-to-balloon times.

Conclusions:

  • Hospital survival for STEMI-CS patients did not differ significantly between centers with and without MCS availability.
  • The availability of MCS in a center does not appear to influence survival outcomes for STEMI-CS patients in this large registry analysis.
Abstract

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