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Response to "Comment on 'Three-Principal-Substrate SERS Profiling Enables Reliable Screening of Serum Biomarkers: A
Xuecheng Dong1, Zhengyuan Zhao1, Weipeng Wang1
1Key Laboratory of Advanced Materials (MOE), School of Materials Science and Engineering, Tsinghua University, Beijing 100084, China.
None:
We sincerely thank Alois Bonifacio and co-workers for their valuable comments on our work entitled "Three-Principal-Substrate SERS Profiling Enables Reliable Screening of Serum Biomarkers: A General Approach" (Anal. Chem. 2026, 98, 9273; DOI: 10.1021/acs.analchem.5c08093). The present response aims to address the concerns raised regarding the interpretation of SERS band assignments, as well as the suggestion that more rigorous validation of differential spectral features should be pursued in future studies.
