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Updated: Jun 26, 2026

Improved Hysteroscopic Resection of Endometrial Polyps Using 6-Fr Micro-Scissors and Forceps
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Improved Hysteroscopic Resection of Endometrial Polyps Using 6-Fr Micro-Scissors and Forceps

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Endometrial Cancer Recurrence Risk Following Robotic Hysterectomy.

Sean Zhu1, Ericka Wiebe2, Haley Frerichs3

  • 1Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Cumming School of Medicine, University of Calgary, Foothills Medical Centre, 1403 29 Street NW, Calgary, AB T2N 2T9, Canada.

Current Oncology (Toronto, Ont.)
|June 25, 2026
PubMed
Summary

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Recurrence after robotic laparoscopic surgery for endometrial cancer is linked to factors like lymphovascular space invasion and tumor stage. Careful consideration of uterine manipulator use is advised to minimize recurrence risk.

Area of Science:

  • Gynecologic Oncology
  • Minimally Invasive Surgery
  • Surgical Oncology

Background:

  • Minimally invasive surgery, particularly robotic laparoscopy, is a standard treatment for endometrial cancer.
  • Despite advancements, cancer recurrence remains a significant concern in endometrial cancer management.

Purpose of the Study:

  • To identify risk factors for recurrence in endometrial cancer patients treated with robotic laparoscopy.
  • To evaluate the impact of surgical techniques and adjuvant therapies on recurrence-free survival.

Main Methods:

  • Retrospective review of 1278 patients undergoing robotic laparoscopic hysterectomy between 2012 and 2019.
  • Multivariate Cox proportional hazards models were used to calculate recurrence-free survival and hazard ratios.
Keywords:
endometrial cancerlymphovascular space invasionrecurrencerobotic hysterectomyuterine manipulator

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Published on: September 12, 2019

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Last Updated: Jun 26, 2026

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An Orthotopic Endometrial Cancer Model with Retroperitoneal Lymphadenopathy Made From In Vivo Propagated and Cultured VX2 Cells
09:48

An Orthotopic Endometrial Cancer Model with Retroperitoneal Lymphadenopathy Made From In Vivo Propagated and Cultured VX2 Cells

Published on: September 12, 2019

Main Results:

  • 155 cases of recurrent disease were identified. Significant risk factors included older age, lymphovascular space invasion (LVSI), advanced stage, and high-grade histology.
  • Uterine manipulator use was an independent risk factor for recurrence (HR 2.12, p < 0.001).
  • Chemoradiotherapy showed a significant reduction in recurrence risk (HR 0.44, p = 0.002), while adjuvant chemotherapy and radiotherapy showed non-significant trends toward reduced risk.

Conclusions:

  • Traditional prognostic factors remain crucial for predicting recurrence in endometrial cancer patients after robotic laparoscopic hysterectomy.
  • The use of a uterine manipulator during surgery is an independent risk factor and warrants careful reconsideration.