Short-Term Cardiac Effects of Bariatric Surgery: Is Weight Loss Alone Sufficient in Metabolically Healthy Morbidly

Omer Ozkan Duman1, Ummu Taş1, Sedat Taş1

  • 1Department of Cardiology, İzmir Demokrasi University, Buca Research and Training Hospital, 35390 İzmir, Turkey.

Insights

Bariatric surgery significantly improves cardiac structure and function in metabolically healthy obese individuals by reducing adipose tissue. This weight loss reverses negative heart remodeling, lowering cardiovascular risk without comorbidities.

Area of Science:

  • Cardiology
  • Bariatric Surgery
  • Obesity Medicine

Background:

  • Obesity is a major cardiovascular disease risk factor.
  • Comorbidities like diabetes and hypertension obscure obesity's direct cardiac impact.
  • The study focuses on metabolically healthy obese (MHO) individuals to isolate obesity's effects.

Purpose of the Study:

  • To evaluate the isolated effects of weight loss from bariatric surgery on left ventricular (LV) geometry and diastolic function.
  • To assess cardiac remodeling in MHO patients post-bariatric surgery.
  • To understand the impact of reduced adipose tissue and hemodynamic load on the heart.

Main Methods:

  • Included 28 MHO patients undergoing Laparoscopic Sleeve Gastrectomy (LSG) (BMI > 40 kg/m²).
  • A control group of 25 MHO patients without surgery was matched for age and gender.
  • Echocardiographic and demographic data were analyzed at baseline and 6 months post-surgery.

Main Results:

  • Surgical group showed significant BMI reduction (46.21 to 37.11 kg/m²) and decreased Left Ventricular Mass Index (51.11 to 44.57 g/m²).
  • Diastolic function improved, indicated by a significant increase in the E/A ratio (1.19 to 1.34).
  • Marked improvements in glucose and lipid profiles were observed in the surgical group.

Conclusions:

  • Bariatric surgery induces cardiac reverse remodeling and improves function in MHO patients, independent of metabolic comorbidities.
  • Weight loss through bariatric surgery directly reduces adipose tissue and alleviates hemodynamic load on the heart.
  • Surgery is effective in reducing cardiovascular risk and preserving cardiac structure in morbidly obese individuals without comorbidities.

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