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The Potential and Prospects of Marine Drugs in Intervening Nerve-Tumor Crosstalk

Dan Zhao1, Ruiling Xu2, Xinyan Xu2

  • 1Basic Medicine Research and Innovation Center for Novel Target and Therapeutic Intervention, College of Pharmacy, Chongqing Medical University, Ministry of Education, Chongqing 400016, China.

Marine Drugs
|June 25, 2026
PubMed

Insights

Marine natural products offer novel strategies for treating cancer by targeting the communication between nerves and tumors. This research explores marine compounds for neuropharmacological agents to manage cancer pain and therapy.

Area of Science:

  • Neuroscience
  • Oncology
  • Pharmacology

Background:

  • The interaction between the nervous system and tumors is a key area in cancer research.
  • Marine natural products possess neuroactive properties beneficial for therapeutic interventions.

Purpose of the Study:

  • To analyze the communication between the nervous system and tumors.
  • To summarize marine-derived molecules' role in neuroscience and cancer treatment.
  • To propose future research directions for marine neuropharmacological agents.

Main Methods:

  • Systematic and prospective dissection of nerve-tumor bidirectional communication.
  • Comprehensive literature review of marine-derived bioactive molecules.
  • Analysis of their impact on neuroscience and antitumor therapeutics.

Main Results:

  • Identified complex bidirectional communication pathways between nerves and malignancies.
  • Highlighted the significant contributions of marine compounds to neuropharmacology and oncology.
  • Established the potential of marine neuropharmacological agents.

Conclusions:

  • Marine natural products are promising for developing therapeutics targeting the nerve-tumor axis.
  • Interdisciplinary collaboration is crucial for advancing marine neuropharmacology.
  • This field holds potential for improved cancer pain management and precision oncotherapy.
Keywords:
cancer painmarine drugsnerve–tumor crosstalkoncotherapy

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