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Updated: Jun 26, 2026

Noninvasive Sampling of Mucosal Lining Fluid for the Quantification of In Vivo Upper Airway Immune-mediator Levels
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Noninvasive Sampling of Mucosal Lining Fluid for the Quantification of In Vivo Upper Airway Immune-mediator Levels

Published on: August 7, 2017

Sex-Specific Differences in Perinatal Risk Factors for Atopic Dermatitis: A Large Retrospective Population-Based

Roosa Moilanen1, Eero Pohjola1, Laura Huilaja2,3

  • 1Faculty of Medicine, University of Oulu, Oulu, Finland.

Acta Paediatrica (Oslo, Norway : 1992)
|June 25, 2026
PubMed
Summary

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This summary is machine-generated.

Low birth weight protects males from developing atopic dermatitis (AD), but this effect is not seen in females. Gestational age and delivery method did not impact AD risk.

Area of Science:

  • Dermatology
  • Pediatrics
  • Epidemiology

Background:

  • Atopic dermatitis (AD) is a common inflammatory skin condition.
  • Understanding risk factors for AD is crucial for prevention and early intervention.
  • Previous research has explored various risk factors, but sex-specific associations require further investigation.

Purpose of the Study:

  • To investigate the association between gestational age at birth, method of delivery, and birth weight with the risk of developing atopic dermatitis (AD).
  • To determine if these associations differ between males and females.

Main Methods:

  • Utilized data from the population-based Northern Finland Birth Cohort 1986.
  • Analyzed data from 8993 subjects, comparing those with and without AD.
Keywords:
atopic dermatitisbirth weightcaesarean sectiongestational agepredisposing factors

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Last Updated: Jun 26, 2026

Noninvasive Sampling of Mucosal Lining Fluid for the Quantification of In Vivo Upper Airway Immune-mediator Levels
05:31

Noninvasive Sampling of Mucosal Lining Fluid for the Quantification of In Vivo Upper Airway Immune-mediator Levels

Published on: August 7, 2017

  • Statistical analysis included adjusted risk ratios and confidence intervals.

    • Main Results:

    • The overall prevalence of AD was 23.7%.
    • Gestational age at birth and method of delivery were not associated with AD risk.
    • Low birth weight was a protective factor against AD in males (RR 0.54), but not in females.

    Conclusions:

    • The study identified sex-specific risk factors for atopic dermatitis.
    • Low birth weight appears to have a protective effect against AD in males only.
    • Further research is warranted to elucidate the mechanisms behind these sex differences.