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Related Concept Videos

Responses to Heat and Cold Stress02:45

Responses to Heat and Cold Stress

Every organism has an optimum temperature range within which healthy growth and physiological functioning can occur. At the ends of this range, there will be a minimum and maximum temperature that interrupt biological processes.
Methods of reducing fever01:22

Methods of reducing fever

The signs and symptoms of fever include hot and dry skin, flushed face, thirst, muscle aches, anorexia, headache, tachycardia, tachypnea, and fatigue. Elevated body temperature is reduced using two methods: pharmacological and nonpharmacological. Proper identification and treatment of the root cause of a fever is of utmost importance.
Pharmacological Methods of Reducing Fever:
Decreased Body Temperature01:29

Decreased Body Temperature

A decreased body temperature can occur in patients with hypothermia and frostbite. Heat loss with extended cold exposure overpowers the body's ability to create heat, resulting in hypothermia. Core temperature readings help classify hypothermia. Mild hypothermia is temperatures between 32 °C (89.6 °F) and 35°C (95 °F) and is caused by impaired thermoregulation. Moderate hypothermia is temperatures between 28 C (82.4 °F) and 32 °C (89.6 °F) caused by sustained extreme cold exposure, and severe...
Homeostatic Imbalances in Body Temperature01:19

Homeostatic Imbalances in Body Temperature

Hyperthermia occurs when the body's temperature becomes unusually high, often due to heat exposure, intense physical activity, or certain illnesses. This condition can create a dangerous cycle where elevated body temperature increases the metabolic rate, generating more heat and potentially leading to organ failure and brain damage. A severe form of hyperthermia, called heat stroke, can raise body temperature to life-threatening levels. Fever, on the other hand, is a controlled form of...
Factors Affecting Body Temperature01:28

Factors Affecting Body Temperature

As a nurse, it is vital to understand the factors affecting body temperature to monitor variations and effectively evaluate deviations from regular.
Factors may  include:
Hot Weather Concreting01:20

Hot Weather Concreting

Concreting at elevated temperatures accelerates the hydration process, leading to quicker setting but potentially reducing the long-term strength of the concrete structure. Additionally, low air humidity fosters rapid moisture loss from the concrete, resulting in reduced workability, pronounced plastic shrinkage, and a higher likelihood of crazing.
Mitigating the heat increase in concrete can be economically achieved by shading aggregate stockpiles to prevent heating from solar radiation,...

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Related Experiment Video

Updated: Jun 26, 2026

Using an Ingestible Telemetric Temperature Pill to Assess Gastrointestinal Temperature During Exercise
08:22

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Published on: October 7, 2015

The ADAPT-HEAT Study: A Multi-Method Approach to Develop Recommendations for Drug Safety During Hot Weather (The

Maxie Bunz1, Pascal Nohl-Deryk1, Heike van de Sand2,3

  • 1Institute of General Practice, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50937 Cologne, Germany.

Methods and Protocols
|June 25, 2026
PubMed
Summary
This summary is machine-generated.

This study develops the CALOR list, providing crucial recommendations for managing heat-sensitive medications during heatwaves. It ensures safer drug administration and protects public health during extreme heat events.

Keywords:
clinical protocolsextreme heathot temperaturepatient safetypotentially inappropriate medication list

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Area of Science:

  • Pharmacology
  • Public Health
  • Environmental Medicine

Background:

  • Heatwaves pose significant risks to public health, exacerbated by medications that can impair heat adaptation or alter physiological balance.
  • Existing guidelines for managing medication safety during extreme heat are insufficient, necessitating a structured approach.

Purpose of the Study:

  • To develop evidence-based, cross-sectoral recommendations for the safe administration of heat-sensitive medications.
  • To create a comprehensive 'CALOR' (calor: Latin for 'heat') list to guide healthcare professionals.

Main Methods:

  • A four-pillar approach: scoping review, expert panel Delphi process, analysis of health insurance claims data linked with climate data, and field-testing by health professionals.
  • Identification of potentially inadequate medications during heat events (heat-PIMs) and development of adaptation measures.

Main Results:

  • The study protocol outlines the systematic development of the CALOR list, integrating scientific literature, expert consensus, real-world data, and practical feedback.
  • The research aims to provide the first comprehensive and actionable recommendations for drug safety during heat events.

Conclusions:

  • The CALOR list will offer critical guidance for healthcare providers to mitigate medication-related risks during heatwaves.
  • This initiative seeks to enhance patient safety and public health resilience in the face of increasing climate challenges.