Related Experiment Video

Updated: Jun 26, 2026

Real-Time Measurements of Calcium and Contractility Parameters in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes
06:42

Real-Time Measurements of Calcium and Contractility Parameters in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes

Published on: May 26, 2023

Sequential changes in calcium transients during M phase regulate cardiomyocyte proliferation

Honghai Liu1, Niyatie Ammanamanchi1, Jocelyn D Mich-Basso2,3

  • 1Department of Pediatrics, Weill Cornell Medical College, Cornell University, New York City, NY, USA.

The Journal of Cell Biology
|June 25, 2026
PubMed
Summary

Cardiomyocyte proliferation involves dynamic changes in calcium transients (CaTs). Reduced Ca2+ at spindle poles, regulated by CDK1 and SERCA2a, is crucial for proper cell division and heart muscle regeneration.

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