Related Experiment Video
Updated: Jun 26, 2026

Separation of Immune Cell Subpopulations in Peripheral Blood Samples from Children with Infectious Mononucleosis
Published on: September 7, 2022
Association between Epstein-Barr Virus viremia and cardiac function in children and young adults with perinatally
Samantha F Curtis1, Andrew W McCrary2, Ibrahim Daud3
1Department of Internal Medicine-Pediatrics, Duke University Medical Center, Durham, NC, USA.
Introduction:
Epstein-Barr virus (EBV) affects greater than 95% of the global population, and when acquired at an early age, results in poor control of viral replication and increased risk to subsequent chronic illnesses.
Objective:
To analye the association between EBV and early cardiac dysfunction.
Methods:
A cross-sectional echocardiographic study on children, adolescent and young adults living with human immunodeficiency virus (HIV) in Eldoret, Kenya. We collected echocardiograms, viral copy levels, and inflammatory markers. We compared EBV-positive participants to EBV-negative participants.
Results:
The majority of patients with EBV copies detected were male, median (25-75%) age of 15 (11-19) years and did not have signs of early cardiac dysfunction. No significant differences were observed in cardiac function between individuals with detectable and undetectable EBV copies (p = 0.472; p = 0.6140; p = 0.382 respectively).
Conclusions:
In this population of individuals, no significant difference in cardiac function between individuals with detectable and undetectable EBV copies was observed.
Related Concept Videos
Cytomegalovirus Disease
Myocarditis III: Medical Management
Poliomyelitis
Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies
Encephalitis l: Introduction
Endocarditis II: Clinical Features of Infective Endocarditis

