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Updated: Jun 26, 2026

An R-Based Landscape Validation of a Competing Risk Model
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An R-Based Landscape Validation of a Competing Risk Model

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Quantifying the Financial Return on Investment of Risk-Based Quality Management Implementation in Clinical

Abigail Dirks1, Sylviane de Viron2, Kenneth McFarlane3

  • 1Tufts Center for the Study of Drug Development, Tufts University School of Medicine, Boston, MA, USA. Abigail.Dirks@tufts.edu.

Therapeutic Innovation & Regulatory Science
|June 25, 2026
PubMed
Abstract

Keywords:
Centralized monitoringClinical trial efficiencyExpected net present valueICH E6(R3)Oncology drug developmentQuality by designReturn on investmentRisk-based quality managementSource data verification

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