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123 I-MIBG SPECT/CT Reveals Solitary Dorsal Root Ganglion Metastasis From Neuroblastoma Mimicking Schwannoma on MRI
Keyu Zhang1, Cinian Lv2, Bingyan Zhang1
1Department of Nuclear Medicine, Beijing Friendship Hospital of Capital Medical University, Xi Cheng.
Abstract:
A 6-year-old girl with high-risk neuroblastoma achieved a complete response following multimodal therapy. During routine post-therapeutic surveillance, 123 I-MIBG SPECT/CT revealed progressive focal tracer uptake within the right T8-T9 intervertebral foramen. Serial imaging demonstrated interval enlargement of the lesion. On contrast-enhanced MRI, the mass exhibited homogeneous hypointensity on T1-weighted images, hyperintensity on T2-weighted images, and intense, uniform enhancement after intravenous gadolinium administration. Radiologic assessment initially favored a schwannoma. Histopathologic examination of the resected specimen confirmed metastatic neuroblastoma involving the dorsal root ganglion.
