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Updated: Jun 27, 2026

Fabrication of Ti3C2 MXene Microelectrode Arrays for In Vivo Neural Recording
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Synthesis and Surface Engineering of Two-Dimensional MXenes for Advanced Functional Applications.

Dalil N H Al-Ghubairi1, Hadi M Marwani1,2, Mahmood D Aljabri3

  • 1Chemistry Department, Faculty of Science, King Abdulaziz University, Jeddah, Saudi Arabia.

Chemical Record (New York, N.Y.)
|June 25, 2026
PubMed
Summary
This summary is machine-generated.

Two-dimensional MXenes (2D MXenes) show great promise for catalysis, energy storage, and sensing due to their unique properties. Recent advances focus on novel synthesis, post-synthesis modifications, and addressing challenges for next-generation technologies.

Keywords:
2D MXenesCVDMAX phasescatalysisenergy storagessensors

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Area of Science:

  • Materials Science
  • Nanotechnology
  • Chemistry

Background:

  • Two-dimensional MXenes (2D MXenes) are a class of transition metal carbides, nitrides, and carbonitrides.
  • They possess metallic conductivity, hydrophilic surfaces, high surface area, and tunable surface terminations.
  • These properties make them suitable for catalysis, sensing, energy storage, and environmental remediation.

Purpose of the Study:

  • To provide a comprehensive overview of recent advances in MXene research since 2020.
  • To discuss synthesis strategies, post-synthesis modifications, and applications of MXenes.
  • To critically analyze challenges and future prospects in MXene development.

Main Methods:

  • Review of conventional top-down etching (e.g., HF etching) and in situ fluoride-based methods.
  • Exploration of safer fluoride-free synthesis routes (electrochemical, hydrothermal, molten-salt etching).
  • Discussion of bottom-up fabrication (CVD, template-assisted growth) and post-synthesis modifications (ALD, solvothermal, microwave-assisted, ball-milling).

Main Results:

  • Recent progress in MXene synthesis, including fluoride-free and bottom-up approaches.
  • Advancements in post-synthesis modification for tailoring MXene properties (interlayer spacing, surface chemistry).
  • Summarized applications in photocatalysis, electrocatalysis, energy storage, and sensors, emphasizing structure-property-performance relationships.

Conclusions:

  • MXenes offer significant potential for advanced applications due to their tunable properties.
  • Key challenges include oxidation, restacking, and scalable, safe production.
  • Future research should focus on overcoming these challenges for next-generation MXene-based devices.